Dermatology, Internal Medicine, Allergology, Cosmetic Dermatology, Cosmetic Internal Medicine

Beautiful Skin Texture Improvement

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This is a revolutionary peeling treatment that strongly promotes collagen production in the dermis without exfoliating the skin surface.
It is also known as a “Collagen Peel” because it increases dermal collagen to improve firmness and elasticity.

Recommended for those who:

  • Loss of skin elasticity
  • Desire for firmness and radiance
  • Concerned about skin dullness
  • Concerned about acne or acne scars
  • Concerned about pores
  • Concerned about stretch marks

What is Massage Peel?

Massage Peel uses an Italian-made peeling agent called PRX-T33®, which contains 33% TCA (trichloroacetic acid), low-concentration hydrogen peroxide, and kojic acid, which has a high whitening effect.

TCA (Trichloroacetic Acid) is a chemical peeling agent with a long history and provides high skin-beautifying effects by acting deep within the skin. However, because it has a strong exfoliating effect on the epidermis and carries a high risk of post-treatment pain, downtime, and post-inflammatory hyperpigmentation, it has been used for partial treatments in Japan but not as a general skin-beautifying treatment.

Massage Peel is a revolutionary peeling treatment that combines TCA (trichloroacetic acid) with hydrogen peroxide to strongly stimulate collagen production in the dermis and restore lost firmness and elasticity without exfoliating the surface. Furthermore, it contains kojic acid, which suppresses the activity of tyrosinase—the cause of spots and dullness—so improvements in whitening and post-inflammatory hyperpigmentation can also be expected.

Additionally, the synergistic effect of combining it with Dermapen 4 brings you closer to smoother, more beautiful “velvet skin.”
Click here for more about “Velvet Skin”

Three Key Ingredients in Massage Peel

33% TCA (Trichloroacetic Acid)

TCA (trichloroacetic acid) acts deep within the skin to promote the proliferation of keratinocytes and fibroblasts, accelerate skin turnover, and restore the barrier function (biorevitalization).
By incorporating hydrogen peroxide, excessive reactions on the skin surface are suppressed, allowing for the stimulation of collagen production in the dermis without exfoliating the skin surface, resulting in firm, elastic, and youthful skin.

Low-Concentration Hydrogen Peroxide

Low-concentration hydrogen peroxide quickly penetrates tissues and protects the epidermis from TCA (trichloroacetic acid). It also enhances the collagen-producing effects of TCA in the dermis and promotes wound healing by improving blood flow.

5% Kojic Acid

Kojic acid suppresses the activation of tyrosinase, the enzyme that produces melanin responsible for spots and dullness. Therefore, it is effective for spots, dullness, melasma, acne scars, and hyperpigmentation.

Case photos

Facial Massage Peel

Hand Massage Peel

Home Care to Enhance Massage Peel Effects

<WiQo Fluido Levigante 30ml>

Contains 8% glycolic acid in a well-balanced formula for the skin.
Despite its low pH of approximately 3, it can be used without experiencing a burning sensation. After a Massage Peel, keeping the skin in a low pH (acidic) state promotes the skin’s regeneration process, making it possible to sustain collagen production for a long period.

<WiQo Nourishing Moisturizing Cream>

A cream with high moisturizing power. It works to restore the hydrolipidic film of skin that has lost firmness or has been affected by aging and external factors (cold, wind, UV rays, etc.). By restoring the hydrolipidic film after a Massage Peel, it repairs the natural skin barrier and prevents the evaporation of moisture from the skin, which can cause issues. It contains shea butter to soothe and protect the skin.

Treatment details

Treatment Interval Once every 2 to 4 weeks; 4 to 5 sessions constitute one course.
Treatment Time 15 minutes for the procedure
Anesthesia None
Downtime Slight redness, a tingling sensation, mild peeling, scabbing, or hyperpigmentation may occur.
Makeup No specific restrictions
Follow-up visits None in particular
Face Washing, Showering, Bathing No specific restrictions
Medication None in particular. Use in conjunction with WiQo home care is recommended.
Recommended Combined Treatments Dermapen 4, Ionophoresis, High-dose Vitamin C Drip
Precautions for the Procedure
  • ・Individuals with dermatitis or severe sunburn
  • ・Individuals with seborrheic dermatitis or herpes
    The procedure cannot be performed on those with allergies to TCA or kojic acid.
  • ・The procedure cannot be performed during pregnancy or while breastfeeding.
  • ・Please refrain from using peeling agents or medications with exfoliating effects, such as RAC (retinoic acid) or Differin Gel, for 1 to 2 weeks before and after the procedure.
  • ・Since the skin becomes delicate after the procedure, please avoid friction and UV rays, and ensure thorough moisturizing.
Applicable Areas Face, neck, décolletage, hands, stretch marks, etc.

Revitalize your natural skin beauty. Experience hydration, firmness, and clarity.
PDRN injections extracted from salmon regenerate damaged or aging skin.
LIZNE is characterized by higher purity compared to conventional PDRN products, making post-treatment redness less likely, and features reduced pain due to its adjusted pH level.

Recommended for those who:

  • Want smoother texture, firmness, and radiance
  • Are concerned about fine lines on the face
  • Are concerned about wrinkles on the neck, décolletage, and backs of the hands
  • Those concerned about acne scars or surgical scars
  • Those who wish to improve deep-set wrinkles that do not respond to Botox

What is LIZNE?

LIZNE is an injectable treatment primarily composed of PDRN (Polydeoxyribonucleotide) extracted from trout of the Salmonidae family. PDRN is approved as a pharmaceutical product in Europe and is widely used in medical settings for wound healing (skin grafts, burns, scars) and in orthopedics for cartilage and ligament injuries. Unlike treatments like hyaluronic acid fillers that physically add volume to make wrinkles less noticeable, LIZNE works directly on the damaged skin itself. It is a new concept in skin cell regeneration therapy that restores healthy, firm, and elastic skin from within by increasing dermal fibroblasts and promoting the regeneration and increase of collagen and elastin.
It is suitable for deep-set wrinkles, scars, fine lines around the eyes, and overall skin texture improvement. While salmon-derived PDRN is highly biocompatible with the human body and has few side effects, it cannot be administered to those with fish or fish egg allergies.

In particular, LIZNE is characterized by low impurity levels, making post-treatment redness less likely, and features less pain than conventional products because the pH of the solution has been adjusted.

Salmon Injection and Collagen Activation
Treatment Areas for Salmon Injection

Activation of Fibroblasts: Activates fibroblasts in the dermis to produce collagen, elastin, and hyaluronic acid, promoting the regeneration of damaged skin.

Angiogenesis: Creates and regenerates capillaries that decrease with age, improving blood flow in the skin.

Anti-inflammatory Effect: Suppresses skin inflammation and improves skin issues caused by inflammation.


Treatment details

Treatment Interval Once every 2 to 3 weeks. 4 to 5 sessions in total.
Treatment Time 15 minutes (per treatment area)
Anaesthesia Topical anaesthesia; block injection upon request
Downtime Redness, swelling, or unevenness may occur immediately after the procedure, but these usually subside within a few hours.
Internal bleeding (bruising) may occur. While it varies by individual, it typically subsides in about 1 to 3 weeks.
Makeup Possible immediately after
Follow-up visits None in particular
Face washing / shower / bathing No restrictions
Medication None in particular
Recommended combination treatments GenesisLimelight ・Tightening Thread Treatments
Post-Treatment Precautions Please refrain from activities such as intense massaging of the injection site for about half a month.
Contraindications Those with fish or fish egg allergies. *Please consult with us in advance if you are pregnant or breastfeeding.

Chemical Peeling

Chemical peeling is a treatment method that exfoliates and removes old keratin from the epidermis to rejuvenate the skin.

The keratin on the skin surface consists of many layers of cells.
Basal cells at the bottom of the epidermis change shape as they are pushed up by new cells from below, eventually becoming the outermost stratum corneum of the epidermis and naturally peeling off. This is called turnover (metabolism). Healthy skin is said to have a turnover cycle of four weeks (28 days).
However, if this turnover is prolonged due to certain causes (such as stress, lifestyle habits, or environmental changes), old keratin accumulates and causes skin dullness. Furthermore, when turnover abnormalities occur in the pores, it leads to clogged pores and acne.

Chemical peeling is a treatment where chemical agents (chemicals) are applied to the skin to cause a chemical reaction that peels away old skin.By removing keratin from the skin surface and pores and stimulating skin regeneration through chemical irritation, many cosmetic benefits can be expected.
Chemical peeling has a long history; it is said that in ancient Egypt, Cleopatra maintained her beautiful skin by bathing in sour milk containing lactic acid.

Recommended for those who:

  • Concerned about acne or acne scars
  • Feeling that pores are clogged
  • Concerned about skin dullness
  • Oily and sticky skin

Four Benefits of Chemical Peeling

  • Removes unnecessary keratin and clogged pores
  • Normalizes skin turnover and promotes skin regeneration
  • Inhibits tyrosinase, which stimulates melanin—the cause of spots
  • Promotes skin regeneration and increases dermal collagen

These effects can be expected to prevent new acne, heal existing acne, improve acne scars early, improve oily skin, make pores less noticeable, improve dullness, and provide whitening effects.

At our clinic, we perform peeling using “Salicylic Acid Macrogol,” which is gentle on the skin. Salicylic acid has the effect of softening and dissolving keratin. Therefore, it has long been used in dermatology as a treatment for keratin. However, if salicylic acid was absorbed through the sebaceous glands, there was a risk of toxicity (such as nausea, hyperventilation, or tinnitus) due to increased salicylic acid concentration in the blood.

The “Salicylic Acid Macrogol” used at our clinic is a strong acid with a salicylic acid concentration of 30% and a pH of 1.7. However, because the affinity of the base material called “Macrogol” used with “Salicylic Acid” is very high, the acid remains almost entirely in the keratin and does not penetrate deep into the skin, eliminating the risk of toxicity.
Furthermore, it thoroughly exfoliates only excess keratin without causing inflammation, so it is relatively low-irritation and suitable for those with delicate skin who might experience redness, itching, or poor skin condition after other peels (such as those using glycolic acid or lactic acid). We will provide a thorough explanation of the agents and procedures during the counseling session, so please feel free to visit us with peace of mind.

Treatment details

Treatment Interval Once every 4 weeks
Treatment Time 15 minutes
Anesthesia None
Downtime None in particular. Some individuals may experience slight redness, a tingling sensation, or mild peeling.
Makeup After 12 hours
Follow-up visits None in particular
Face Washing, Showering, Bathing No restrictions. (Please do not use facial cleansers with scrubs or peeling effects.)
Medication None in particular
Recommended combination treatments Iontophoresis, Limelight, Spectra, Genesis
Post-Treatment Precautions If you have a sunburn, the possibility of skin trouble increases, so we recommend undergoing the treatment after the sunburn has subsided to some extent.
Precautions
  • • We may decline treatment for those with dermatitis, sunburn, aspirin asthma, or aspirin allergies.
  • • For those who are pregnant, the skin becomes more sensitive, and reactions not normally seen may occur.
  • • Please refrain from using agents with exfoliating effects, such as peeling agents, RAC (retinoic acid), or Differin Gel (acne treatment), for one week before and after the procedure.
  • • Since the skin is delicate after the procedure, do not rub it strongly, avoid UV rays, and ensure thorough moisturizing.

Iontophoresis
Vitamin C Tranexamic Acid

Iontophoresis can enhance the effects of all treatments by delivering and allowing active ingredients to penetrate deeper into the skin.

Recommended for those who:

  • Those suffering from acne or skin irritation
  • Those who want beautiful skin or are concerned about skin quality improvement
  • Those concerned about skin dullness or sagging
  • Those concerned about skin dryness or fine lines

The skin surface has a barrier function to prevent foreign substances from entering the body, so no matter how good an ingredient is for the skin, it cannot penetrate deep into the skin simply by being applied. Iontophoresis is a treatment that uses a weak electric current to allow ionized active ingredients to penetrate “deeper” and “more thoroughly” into the skin. Iontophoresis is highly effective in allowing active ingredients for beautiful skin to penetrate from the basal layer at the bottom of the epidermis to the dermis layer, removing active oxygen, suppressing and discharging melanin pigment (the source of spots), improving pigmentation, improving acne and acne scars, and promoting the production of elastin and collagen that improve skin firmness and texture. After chemical peeling or skin-beautifying laser treatments, skin metabolism becomes active, and skin cells require a lot of nutrients. While the skin is in a state of trying to produce large amounts of collagen and elastin internally and discharge melanin pigment faster due to laser treatment, these processes may not be carried out properly if nutrients are insufficient. Therefore, our clinic recommends receiving iontophoresis as a set, as it can also be expected to supplement the skin with nutrients.

About Iontophoresis Agents

  • Vitamin C
    Vitamin C suppresses melanin production and improves spots, dullness, and post-inflammatory hyperpigmentation left after insect bites or rashes. Furthermore, it removes active oxygen through its antioxidant effect and suppresses the activity of sebaceous glands, making it effective for acne and the redness of acne scars.
  • Tranexamic Acid
    Tranexamic acid suppresses melanin production and works to prevent spots and melasma. It also has an anti-inflammatory effect and is recommended for those concerned about skin irritation. By allowing tranexamic acid to penetrate deep into the skin through iontophoresis, it leads to beautiful skin with a sense of transparency. Using it in combination with Vitamin C results in even brighter skin.

Treatment details

Treatment Interval Approximately once every 1 to 2 weeks
Treatment Time 15 minutes
Anesthesia None
Downtime None in particular
Makeup Immediately after
Follow-up visits None in particular
Face washing / shower / bathing No restrictions
Medication None in particular
Recommended Combined Treatments
Pre-Treatment Precautions Please remove metal items such as accessories and attachments like hearing aids during the procedure.
Those with pacemakers, those who are pregnant, those with heart disease, and those with arrhythmia currently under medication or outpatient care cannot receive the treatment.