Revitalize your natural skin beauty. Experience hydration, firmness, and clarity.
PDRN injections extracted from salmon regenerate damaged or aging skin.
LIZNE is characterized by higher purity compared to conventional PDRN products, making post-treatment redness less likely, and features reduced pain due to its adjusted pH level.
Recommended for those who:
- Want smoother texture, firmness, and radiance
- Are concerned about fine lines on the face
- Are concerned about wrinkles on the neck, décolletage, and backs of the hands
- Those concerned about acne scars or surgical scars
- Those who wish to improve deep-set wrinkles that do not respond to Botox
What is LIZNE?
LIZNE is an injectable treatment primarily composed of PDRN (Polydeoxyribonucleotide) extracted from trout of the Salmonidae family. PDRN is approved as a pharmaceutical product in Europe and is widely used in medical settings for wound healing (skin grafts, burns, scars) and in orthopedics for cartilage and ligament injuries. Unlike treatments like hyaluronic acid fillers that physically add volume to make wrinkles less noticeable, LIZNE works directly on the damaged skin itself. It is a new concept in skin cell regeneration therapy that restores healthy, firm, and elastic skin from within by increasing dermal fibroblasts and promoting the regeneration and increase of collagen and elastin.
It is suitable for deep-set wrinkles, scars, fine lines around the eyes, and overall skin texture improvement. While salmon-derived PDRN is highly biocompatible with the human body and has few side effects, it cannot be administered to those with fish or fish egg allergies.
In particular, LIZNE is characterized by low impurity levels, making post-treatment redness less likely, and features less pain than conventional products because the pH of the solution has been adjusted.
Activation of Fibroblasts: Activates fibroblasts in the dermis to produce collagen, elastin, and hyaluronic acid, promoting the regeneration of damaged skin.
Angiogenesis: Creates and regenerates capillaries that decrease with age, improving blood flow in the skin.
Anti-inflammatory Effect: Suppresses skin inflammation and improves skin issues caused by inflammation.
Treatment details
| Treatment Interval | Once every 2 to 3 weeks. 4 to 5 sessions in total. |
|---|---|
| Treatment Time | 15 minutes (per treatment area) |
| Anaesthesia | Topical anaesthesia; block injection upon request |
| Downtime | Redness, swelling, or unevenness may occur immediately after the procedure, but these usually subside within a few hours. Internal bleeding (bruising) may occur. While it varies by individual, it typically subsides in about 1 to 3 weeks. |
| Makeup | Possible immediately after |
| Follow-up visits | None in particular |
| Face washing / shower / bathing | No restrictions |
| Medication | None in particular |
| Recommended combination treatments | ・Genesis ・Limelight ・Tightening Thread Treatments |
| Post-Treatment Precautions | Please refrain from activities such as intense massaging of the injection site for about half a month. |
| Contraindications | Those with fish or fish egg allergies. *Please consult with us in advance if you are pregnant or breastfeeding. |